Author

V. Horsley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Q. Phan· 2 shared R. Driskell· 2 shared T. Sandoval-Schaefer· 2 shared A. D. Hyder-Wright· 1 shared A. M. Collins· 1 shared A. Prassinos· 1 shared A. R. Jussila· 1 shared A. Zieman· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Q. Phan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Transcriptional heterogeneity in diabetic foot wounds

T. Sandoval-Schaefer, Q. Phan, B. Dash, A. Prassinos, K. Duan, M. I. Gazes, S. D. Vyce, H. C. Hsai, R. Driskell, V. Horsley

This study uses single-cell RNA sequencing to identify transcriptional changes in diabetic foot ulcers compared to non-diabetic wounds, revealing defects in keratinocyte differentiation, fibroblast function, and macrophage metabolism.

bioRxiv · Feb 16, 2023 · PreprintCell Biology

Apoptosis recognition receptors regulate skin tissue repair in mice

O. Justynski, K. Bridges, W. Krause, M. F. Forni, Q. Phan, T. Sandoval-Schaefer, R. Driskell, K. Miller-Jensen, V. Horsley

The paper investigates the role of apoptosis recognition receptors in skin wound repair using mouse models and single-cell RNA sequencing, finding that Axl signaling is critical for repair while Timd4 is essential for efferocytosis.

bioRxiv · Jan 17, 2023 · PreprintCell Biology

Adipocyte lipolysis abrogates skin fibrosis in a Wnt/DPP4-dependent manner

A. R. Jussila, E. Caves, B. Zhang, S. Kirti, M. Steele, V. Lei, E. Hamburg-Shields, J. Lydon, Y. Ying, R. Lafyatis, S. Rajagopalan, V. Horsley, R. P. Atit

This study shows that adipocyte lipolysis, regulated by Wnt signaling and DPP4, reduces skin fibrosis by modulating ECM homeostasis.

bioRxiv · Jan 21, 2021 · PreprintCell Biology

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

E. Carley, R. M. Stewart, A. Zieman, I. Jalilian, D. E. King, A. Zubek, S. Lin, V. Horsley, M. C. King

This study shows that the LINC complex transmits integrin-generated tension to the nuclear lamina, repressing epidermal differentiation in stem cells.

bioRxiv · May 3, 2020Cell Biology

Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan

J. Reine, B. F. Carniel, C. Solorzano, E. Mitsi, S. Pojar, E. Nikolau, E. L. German, A. D. Hyder-Wright, H. Hill, C. Hales, L. Brown, V. Horsley, L. Hughes, S. Zaidi, V. Connor, , S. P. Jochems

This study examines age-related changes in nasal mucosal immune composition and function, finding reduced granulocytes and T cells in young children and older adults, and links pneumococcal colonization to inflammation.

bioRxiv · Mar 14, 2019 · PreprintImmunology