Novel virus-like particle vaccine encoding the circumsporozoite protein of Plasmodium falciparum is immunogenic and induces functional antibody responses
L. Kurtovic, D. Wetzel, L. Reiling, D. R. Drew, C. Palmer, B. Kouskousis, E. Hanssen, B. D. Wines, P. M. Hogarth, M. Suckow, V. Jenzelewski, M. Piontek, J.-A. Chan, J. Beeson
This paper describes a novel virus-like particle vaccine using duck hepatitis B virus surface antigen to display Plasmodium falciparum CSP, showing improved immunogenicity and functional antibody responses in mice.
bioRxiv · Dec 14, 2020Immunology