Author

B. D. Wines

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

J.-A. Chan· 3 shared D. R. Drew· 2 shared J. Beeson· 2 shared L. Kurtovic· 2 shared M. Hogarth· 2 shared M. J. Boyle· 2 shared P. M. Hogarth· 2 shared A. SheelaNair· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

J.-A. Chan

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4 papers

Recent·Most cited

Accurate determination of house dust mite sensitization in asthma and allergic rhinitis through cytometric detection of Der p 1 and Der p 2 binding on Basophils (CytoBas)

L. Hsin, N. Varese, P. M. Aui, B. D. Wines, L. Mascarell, P. M. Hogarth, M. Hew, R. E. O'Hehir, M. C. van Zelm

This paper introduces the CytoBas assay, a flow cytometry method using fluorescent allergen tetramers to detect HDM sensitization in basophils, showing high sensitivity and specificity for Der p 1 and Der p 2.

bioRxiv · Aug 15, 2023Immunology

Age dependent changes in circulating Tfh cells influence the development of functional antibodies to malaria in children.

J.-A. Chan, J. Loughland, L. de la Parte, S. Okano, I. Ssewanyana, M. Nalubega, F. Nankya, K. Musinguzi, J. Rek, E. Arinaitwe, P. Tipping, P. Bourke, D. Andrew, N. Dooley, A. SheelaNair, , M. J. Boyle

The paper examines age-related changes in Tfh cells and their impact on antibody development against malaria in children, finding age-dependent shifts in Tfh cell subsets and antibody responses.

bioRxiv · Dec 12, 2021Immunology

Novel virus-like particle vaccine encoding the circumsporozoite protein of Plasmodium falciparum is immunogenic and induces functional antibody responses

L. Kurtovic, D. Wetzel, L. Reiling, D. R. Drew, C. Palmer, B. Kouskousis, E. Hanssen, B. D. Wines, P. M. Hogarth, M. Suckow, V. Jenzelewski, M. Piontek, J.-A. Chan, J. Beeson

This paper describes a novel virus-like particle vaccine using duck hepatitis B virus surface antigen to display Plasmodium falciparum CSP, showing improved immunogenicity and functional antibody responses in mice.

bioRxiv · Dec 14, 2020Immunology

Multi-functional antibodies are induced by the RTS,S malaria vaccine and associated with protection in a phase I/IIa trial

L. Kurtovic, T. Atre, G. Feng, B. D. Wines, J.-A. Chan, M. J. Boyle, D. R. Drew, M. Hogarth, F. J. I. Fowkes, E. S. Bergmann-Leitner, J. G. Beeson

This study shows RTS,S malaria vaccine induces functional anti-CSP antibodies associated with reduced parasitemia after challenge.

bioRxiv · Nov 22, 2019Immunology