Author

V. M. Howieson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:plant (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

C. Spry· 2 shared E. T. Tjhin· 2 shared K. J. Saliba· 2 shared A. E. Sexton· 1 shared A. G. Maier· 1 shared A. Hoegl· 1 shared A. L. Sewell· 1 shared D. J. Creek· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiochemistry

C. Spry

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2 papers

Recent·Most cited

A novel heteromeric pantothenate kinase complex in apicomplexan parasites

E. T. Tjhin, V. M. Howieson, C. Spry, G. G. van Dooren, K. J. Saliba

The paper identifies heteromeric pantothenate kinase complexes in Plasmodium falciparum and Toxoplasma gondii, showing that PanK1 and PanK2 form functional complexes with Pf14-3-3I and are essential for parasite proliferation.

bioRxiv · Mar 16, 2021Biochemistry

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

E. T. Tjhin, C. Spry, A. L. Sewell, A. Hoegl, L. Barnard, A. E. Sexton, V. M. Howieson, A. G. Maier, D. J. Creek, E. Strauss, R. Marquez, K. Auclair, K. J. Saliba

The paper identifies mutations in Plasmodium falciparum pantothenate kinase genes that confer resistance to pantothenate analogues and reveal different mechanisms of action for these compounds.

bioRxiv · Jul 24, 2017Pharmacology & Toxicology