Author

V. O'Donnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

M. Aldrovandi· 2 shared P. Rodrigues· 2 shared P. Taylor· 2 shared R. Andrews· 2 shared V. Tyrrell· 2 shared A. Cardus Figueras· 1 shared A. O'Connor· 1 shared A. Price· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

M. Aldrovandi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Th1 cells alter the inflammatory signature of IL-6 by channeling STAT transcription factors to Alu-like retroelements

D. Millrine, A. Cardus Figueras, J. Uceda Fernandez, R. Andrews, B. Szomolay, B. C. Cossins, C. Rice, J. Li, V. Tyrrell, L. mcLeod, P. Holmans, V. O'Donnell, P. Taylor, S. J. Turner, B. J. Jenkins, , S. A. Jones

The paper investigates how IFN-gamma-secreting CD4+ T-cells alter the transcriptional output of IL-6 by redirecting STAT1 and STAT3 to Alu-like retroelements during inflammation.

bioRxiv · Jul 18, 2022 · PreprintImmunology

The Virucidal Efficacy of Oral Rinse Components Against SARS-CoV-2 In Vitro

E. Statkute, A. Rubina, V. O'Donnell, D. Thomas, R. J. Stanton

This study tests the virucidal efficacy of oral rinses against SARS-CoV-2 in vitro, finding that some formulations achieve significant virus inactivation.

bioRxiv · Nov 13, 2020Microbiology

Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.

M. Misheva, K. Kotzamanis, L. Davies, V. Tyrrell, P. Rodrigues, G. Benavides, H. Christine, R. Murphy, P. Kennedy, P. Taylor, M. Rosas, S. Jones, J. McLaren, S. Deshpande, R. Andrews, , V. O'Donnell

This study shows that mitochondrial β-oxidation removes oxylipins during bacterial inflammation, with CPT1 playing a key role, and identifies associated genetic upregulation in human sepsis.

bioRxiv · Aug 17, 2020Biochemistry

LipidFinder 2.0: advanced informatics pipeline for lipidomics discovery applications

J. Alvarez-Jarreta, P. Rodrigues, E. Fahy, A. O'Connor, A. Price, C. Gaud, S. Andrews, P. Benton, G. Siuzdak, J. Hawksworth, M. Valdivia, S. Allen, V. O'Donnell

LipidFinder 2.0 improves lipidomics analysis with new modules for artefact filtering, isotope deletion, and FDR assessment, showing better performance than existing tools.

bioRxiv · Aug 16, 2020Biochemistry

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

R. J. Evans, K. Pline, C. Loynes, S. Needs, M. Aldrovandi, J. Tifenbach, E. Bielska, R. Rubino, C. Nicol, R. C. May, H. Krause, V. O'Donnell, S. Renshaw, S. Johnston

bioRxiv · Jan 23, 2019Microbiology