Barcoded Competitive Clone-Initiating Cell (BC-CIC) Analysis Reveals Differences in Ovarian Cancer Cell Genotype and Niche Specific Clonal Fitness During Growth and Metastasis In Vivo
S. M. M. Aalam, X. Tang, J. Song, J. N. Bakkum-Gamez, M. E. Sherman, U. Ray, V. Shridhar, K. R. Kalari, D. J. H. F. Knapp, N. Kannan
This paper introduces a clonal tracking system using DNA barcoding and computational analysis to study metastatic clone fitness and genotype effects in ovarian cancer.
bioRxiv · Apr 8, 2021Cancer Biology