Author

V. Stancheva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1

Frequent Co-Authors

E. A. Miller· 3 shared B. Santhanam· 2 shared M. M. Babu· 2 shared X.-H. Li· 2 shared A. Essafi· 1 shared A. Krishnakumar· 1 shared A. Murthy· 1 shared B. Leslie· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiophysics

E. A. Miller

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Author profile →

4 papers

Recent·Most cited

A molecular mechanism for membrane chaperoning by a late embryogenesis abundant protein

X.-H. Li, C. W. H. Yu, N. Gomez-Navarro, V. Stancheva, H. Zhu, C. Guibao, B. Xie, A. Murthy, M. Wozny, B. Leslie, M. Kaminski, K. Malhotra, C. M. Johnson, M. Blackledge, B. Santhanam, , M. M. Babu

This paper identifies HeLEA1, a tardigrade LEA protein that acts as a mitochondrial membrane chaperone, improving stress tolerance in yeast by stabilizing lipid packing and reducing surface tension.

bioRxiv · Jul 29, 2022Biophysics

Structures of core eukaryotic protein complexes

I. R. Humphreys, J. Pei, M. Baek, A. Krishnakumar, I. Anishchenko, S. R. Ovchinnikov, J. Zheng, T. Ness, S. Banjade, S. R. Bagde, V. Stancheva, X. Li, K. Liu, Z. Zheng, D. Barerro, , D. Baker

The paper uses coevolution analysis and deep learning to model core eukaryotic protein complexes in yeast, identifying 104 new assemblies and structurally characterizing 608 previously unknown complexes.

bioRxiv · Sep 30, 2021Biochemistry

A multivalent fuzzy interface drives reversible COPII coat assembly.

E. A. Miller, V. Stancheva, J. Hutchings, X.-H. Li, B. Santhanam, G. Zanetti, M. M. Babu

The paper investigates how the COPII coat assembles and disassembles through multivalent interactions, revealing design principles for reversible vesicle formation.

bioRxiv · Apr 15, 2020Cell Biology

Tumour suppressor WT1 regulates the let-7-Igf1r axis in kidney mesenchyme

R. Bharathavikru, J. Slight, S. Aitken, G. Petrovich, J. Charlton, V. Stancheva, A. Essafi, K. Pritchard Jones, N. Hastie

The paper shows that WT1 regulates the let-7-Igf1r axis in kidney mesenchyme, linking WT1 mutations to Wilms Tumour through microRNA and IGF signalling disruption.

bioRxiv · Oct 30, 2019 · PreprintCancer Biology