Author

V. Varadan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Singh· 3 shared D. Babu· 2 shared K. Guda· 2 shared P. Joseph· 2 shared T. LaFramboise· 2 shared A. Chak· 1 shared A. E. Blum· 1 shared A. M. Kresak· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersCancer Biology

S. Singh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SYS-Mut: Decoding the Functional Significance of Rare Somatic Mutations in Cancer

S. Khalighi, P. Joseph, D. Babu, S. Singh, T. LaFramboise, K. Guda, V. Varadan

SYS-Mut identifies functional significance of rare somatic mutations in cancer by integrating multi-omic data, revealing lipidogenic networks as therapeutic targets in HNSC.

bioRxiv · Sep 3, 2021 · PreprintCancer Biology

The EphB2-MYC Axis is a Major Determinant of Barrett's Pathobiology and a Therapeutic Vulnerability in Esophageal Cancer

S. Venkitachalam, D. Babu, D. Ravillah, R. M. Katabathula, P. Joseph, S. Singh, B. Udhayakumar, Y. Miao, O. Martinez-Uribe, J. A. Hogue, A. M. Kresak, D. Dawson, T. LaFramboise, J. E. Willis, A. Chak, , K. Guda

This study identifies the EphB2-MYC axis as a key driver of Barrett's Esophagus progression to esophageal adenocarcinoma and a potential therapeutic target.

bioRxiv · May 13, 2021 · PreprintCancer Biology

Cell Surface Multimeric Assemblies Regulate Canonical and Noncanonical EphA2 Receptor Tyrosine Kinase Signaling

X. Shi, R. Lingerak, C. Herting, Y. Ge, S. Kim, P. Toth, C. Cuizon, J. Zheng, L. H. Chao, K. Sossey-Alaoui, M. Buck, S. Singh, V. Varadan, J. Himanen, D. Hambardzumyan, , B. Wang

This study identifies molecular interfaces that mediate EphA2 receptor assembly and distinguishes between canonical and noncanonical signaling pathways.

bioRxiv · Apr 11, 2021 · PreprintBiophysics