Author

C. Herting

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

D. Hambardzumyan· 2 shared A. Angione· 1 shared A. M. Tsankov· 1 shared A. W. Smith· 1 shared B. Giotti· 1 shared B. Wang· 1 shared C. Cuizon· 1 shared C. Paulos· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

D. Hambardzumyan

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3 papers

Recent·Most cited

Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy

N. K. Horvat, I. Karpovsky, M. Wyatt, M. A. Hall, M. Phillips, C. Herting, J. Hammons, Z. Mahdi, R. A. Moffitt, C. Paulos, G. B. Lesinski

This study compares two orthotopic PDAC mouse models to evaluate their suitability for studying adoptive T cell therapy, finding that the MT-5 model better replicates the stromal features of human PDAC.

bioRxiv · Sep 7, 2023 · PreprintCancer Biology

A paracrine circuit of IL-1b/IL-1R1 between myeloid and tumor cells drives glioblastoma progression

Z. Chen, B. Giotti, M. Kaluzova, C. Herting, G. Pinero, m. p. vallcorba, S. Cristea, J. L. Ross, J. Ackley, V. Maximov, F. Szulzewsky, M. Marquez-Ropero, A. Angione, N. Nichols, N. Tsankkova, , D. Hambardzumyan

The paper identifies a paracrine IL-1β/IL-1R1 circuit between myeloid and tumor cells that drives glioblastoma progression and shows that antagonizing this circuit reduces tumor growth and extends survival.

bioRxiv · Apr 3, 2022 · PreprintCancer Biology

Cell Surface Multimeric Assemblies Regulate Canonical and Noncanonical EphA2 Receptor Tyrosine Kinase Signaling

X. Shi, R. Lingerak, C. Herting, Y. Ge, S. Kim, P. Toth, C. Cuizon, J. Zheng, L. H. Chao, K. Sossey-Alaoui, M. Buck, S. Singh, V. Varadan, J. Himanen, D. Hambardzumyan, , B. Wang

This study identifies molecular interfaces that mediate EphA2 receptor assembly and distinguishes between canonical and noncanonical signaling pathways.

bioRxiv · Apr 11, 2021 · PreprintBiophysics