Iva Dundović

The paper shows that polyploid cells in intestinal regeneration are cleared through mitotic errors despite centrosome clustering, leading to rapid loss of faulty lineages.

The paper identifies a universal scaling law for mitotic spindles across eukaryotes, showing metaphase plate width scales with genome size following a power law with an exponent of ~1/3, driven by chromosome crowding.

The study identifies genetic determinants of reproductive aging linked to egg aneuploidy by analyzing maternal exomes and shows kinesin gene variants contribute to aneuploidy and accelerated aging.