Author

Varun Jayeshkumar Shah

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ivan ĐikićiD· 2 shared Thorsten MosleriD· 2 shared Alberto CristianiiD· 1 shared Arghya DuttaiD· 1 shared Betül Toker· 1 shared Borna MarkusiciD· 1 shared Chiara BechtiD· 1 shared Cosmin TudoseiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Ivan ĐikićORCID

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2 papers

Recent·Most cited

ProxiCapture Reveals Context-Dependent CRBN Interactome Landscape of Molecular Glue Degraders

Rubina S. Kazi, H. Bailey, Jan Gerhartz, Varun Jayeshkumar Shah, Betül Toker, Julia Bein, Peter Johannes Wild, Radosław P. Nowak, Thorsten Mosler, Ivan Đikić

ProxiCapture identifies context-dependent CRBN interactors of molecular glues across diverse cell types and tissues, revealing a comprehensive atlas of pomalidomide targets.

Disease and Therapeutics · Jan 1, 2026Peer-reviewedCancer Biology

Multi-scale classification decodes the complexity of the human E3 ligome

Arghya Dutta, Alberto Cristiani, Siddhanta V. Nikte, Jonathan Eisert, Yves Matthess, Borna Markusic, Cosmin Tudose, Chiara Becht, Ronay Çetin, Varun Jayeshkumar Shah, Thorsten Mosler, Koraljka Husnjak, Ivan Đikić, Manuel Kaulich, Ramachandra M. Bhaskara

This paper constructs a comprehensive annotated dataset of human E3 ligases and uses a hierarchical classification framework to analyze their functional and structural relationships.

Nature Communications · Dec 25, 2025Peer-reviewedBioinformatics