Integrative enhancer discovery identifies functional enhancer dependencies in pediatric acute myeloid leukemia
Leah Schüler, Robert E. Winkler, José Gonçalves-Dias, K Schuschel, Hasan Issa, Lonneke Verboon, Xiaoyan Wei, Ronay Çetin, Yves Matthess, Manuel Kaulich, Stefan Hüttelmaier, Raj Bhayadia, Dirk Heckl, Jan‐Henning Klusmann
This study identifies functional enhancer dependencies in pediatric AML using an integrative approach, revealing H-ME as an RNA-independent regulator of MYB.
bioRxiv · Aug 21, 2026 · PreprintCancer Biology