Author

Vernon B Carruthers

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alfredo J. GuerraiD· 1 shared Aline Sardinha-SilvaiD· 1 shared Beth Gregg· 1 shared Bethany B. MooreiD· 1 shared Björn F.C. KafsackiD· 1 shared Michael E. GriggiD· 1 shared Stephen J. GurczynskiiD· 1 shared Stephen RavertyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperMicrobiology

Alfredo J. GuerraORCID

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1 paper

Recent·Most cited

Toxoplasma induced cytokine release syndrome is critically dependent on the expression of pore-forming Perforin-Like Protein-1

Beth Gregg, Alfredo J. Guerra, Stephen Raverty, Aline Sardinha-Silva, Björn F.C. Kafsack, Tracey L. Schultz, Stephen J. Gurczynski, Bethany B. Moore, Vernon B Carruthers, Michael E. Grigg

This study shows that Toxoplasma gondii's PLP1 protein drives cytokine release syndrome by inducing dysregulated immune responses, leading to lethal inflammation during acute infection.

bioRxiv · Mar 17, 2025 · PreprintMicrobiology