Author

Vijayalalitha Ramanarayanan

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Philipp OberdoerfferiD· 2 shared Bhushan L Thakur· 1 shared Colina X. Qiao· 1 shared David CorujoiD· 1 shared Laura BaranelloiD· 1 shared Marcus BuschbeckiD· 1 shared Marina FarkašiD· 1 shared Pedro J. BatistaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Philipp OberdoerfferORCID

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2 papers

Recent·Most cited

G quadruplex DNA facilitates a pervasive path to homologous recombination

Bhushan L Thakur, Priyanka Basak, Simran Khurana, Shalu Sharma, Yen-Hsi Lai, Tai Nguyen, Vijayalalitha Ramanarayanan, XianZhen Zhao, Pedro J. Batista, Travis H. Stracker, Philipp Oberdoerffer

This study identifies G-quadruplex DNA as a key factor in homologous recombination, showing that DHX36 suppresses G4-mediated HR and its loss enhances repair and promotes ALT.

bioRxiv · Jun 7, 2026 · PreprintMolecular Biology

Epigenetic control of Topoisomerase 1 activity presents a cancer vulnerability

Tae-Hee Lee, Colina X. Qiao, Vladislav Kuzin, Yubo Shi, Marina Farkaš, Zhiyan Zhao, Vijayalalitha Ramanarayanan, Tongyu Wu, Tianyi Guan, Xianzhen Zhou, David Corujo, Marcus Buschbeck, Laura Baranello, Philipp Oberdoerffer

The paper identifies macroH2A1 splicing as a regulator of TOP1 activity and shows its impact on cancer vulnerability to TOP1 inhibitors.

Nature Communications · Aug 12, 2025Peer-reviewedMolecular Biology