Author

W. C. Peng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

E. Duiker· 2 shared J. J. Molenaar· 2 shared J. Zsiros· 2 shared A. Janse· 1 shared B. B. J. Tops· 1 shared D. J. Munter· 1 shared D. Krijgsman· 1 shared E. T. P. Verwiel· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

E. Duiker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors

I. A. E. M. van Belzen, M. C. van Tuil, S. Badloe, A. Janse, E. T. P. Verwiel, M. Santoso, S. de Vos, J. Baker-Hernandez, H. H. D. Kerstens, N. Solleveld-Westerink, M. T. Meister, J. Drost, M. M. van den Heuvel-Eibrink, J. H. M. Merks, J. J. Molenaar, , J. Y. Hehir-Kwa

The paper identifies prevalent and pathogenic complex structural variations in pediatric solid tumors, linking them to adverse clinical outcomes and potential therapeutic targets.

bioRxiv · Sep 19, 2023Cancer Biology

Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities

T. A. Kluiver, Y. Lu, S. A. Schubert, L. J. Kraaier, F. Ringnalda, P. Lijnzaad, J. DeMartino, W. L. Megchelenbrink, V. Amo-Addae, S. Eising, F. W. de Faria, D. J. Munter, M. van de Wetering, K. Kerl, E. Duiker, , W. C. Peng

This study identifies two hepatoblastoma subtypes with distinct WNT activation profiles and discovers drug sensitivities in patient-derived tumor organoids.

bioRxiv · Aug 28, 2023 · PreprintCancer Biology

Hepatoblastoma exhibits a predominantly myeloid immune landscape and reveals opportunities for macrophage targeted immunotherapy

D. Krijgsman, L. Kraaier, M. Verdonschot, S. Schubert, J. Leusen, E. Duiker, R. de Kleine, V. de Meijer, R. de Krijger, J. Zsiros, W. C. Peng, Y. Vercoulen

This paper characterizes the immune landscape of hepatoblastoma, revealing a myeloid-dominated environment with limited T cells and opportunities for macrophage-targeted immunotherapy.

bioRxiv · Jun 28, 2023Cancer Biology