Author

R. de Krijger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Groenendijk· 1 shared A. J. R. Heck· 1 shared A. Janse· 1 shared A. M. Cornel· 1 shared A. Rodriguez· 1 shared A. Sanchez-Bernabeu· 1 shared B. B. Tops· 1 shared D. F. van der Leest· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Groenendijk

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3 papers

Recent·Most cited

Hepatoblastoma exhibits a predominantly myeloid immune landscape and reveals opportunities for macrophage targeted immunotherapy

D. Krijgsman, L. Kraaier, M. Verdonschot, S. Schubert, J. Leusen, E. Duiker, R. de Kleine, V. de Meijer, R. de Krijger, J. Zsiros, W. C. Peng, Y. Vercoulen

This paper characterizes the immune landscape of hepatoblastoma, revealing a myeloid-dominated environment with limited T cells and opportunities for macrophage-targeted immunotherapy.

bioRxiv · Jun 28, 2023Cancer Biology

Molecular characterization reveals subclasses of 1q gain in intermediate-risk Wilms tumors

I. A. van Belzen, M. van Tuil, S. Badloe, E. Strengman, A. Janse, E. T. Verwiel, D. F. van der Leest, S. de Vos, J. L. Baker-Hernandez, A. Groenendijk, R. de Krijger, H. H. Kerstens, J. Drost, M. M. van den Heuvel-Eibrink, B. B. Tops, , J. Y. Hehir-Kwa

The paper identifies subclasses of 1q gain in Wilms tumors by integrating genomic and expression data, revealing differences in mutational mechanisms and functional effects.

bioRxiv · Aug 12, 2022 · PreprintCancer Biology

Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

J. Wienke, L. L. Visser, W. M. Kholosy, K. M. Keller, M. Barisa, S. Munnings-Tomes, E. Carlton, E. Poon, A. Rodriguez, R. Bernardi, F. Van den Ham, S. R. Van Hooff, Y. A. H. Matser, M. Tas, K. P. S. Langenberg, , J. J Molenaar

The paper uses single-cell RNA sequencing to analyze neuroblastoma and identifies the NECTIN2-TIGIT axis as a potential target for immunotherapy.

bioRxiv · Jul 15, 2022Cancer Biology