Author

W. F. Bohler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:rat· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Okumura· 3 shared C. Shaia· 3 shared F. Feldmann· 3 shared H. Feldmann· 3 shared K. Rosenke· 3 shared J. Lovaglio· 2 shared K. Meade-White· 2 shared M. Jarvis· 2 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

A. Okumura

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Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 Omicron BA.1 and BA.2 are attenuated in rhesus macaques as compared to Delta

N. van Doremalen, M. Singh, T. Saturday, K. C. Yinda, L. Perez-Perez, W. F. Bohler, Z. Weishampel, M. Lewis, J. Schulz, B. Williamson, K. Meade-White, S. Gallogly, A. Okumura, F. Feldmann, J. Lovaglio, , K. Rosenke

This study compares disease severity and viral load in rhesus macaques infected with SARS-CoV-2 Delta, Omicron BA.1, and BA.2 variants, finding Omicron variants cause less severe disease with lower viral loads.

Science Advances · Nov 16, 2022Peer-reviewedMicrobiology

Combined Molnupiravir and Nirmatrelvir Treatment Improves the Inhibitory Effect on SARS-CoV-2 in Rhesus Macaques

K. Rosenke, M. Lewis, F. Feldmann, E. Bohrnsen, B. Schwarz, A. Okumura, W. F. Bohler, J. Callison, C. Shaia, C. Bosio, J. Lovaglio, G. Saturday, M. Jarvis, H. Feldmann

The combination of molnupiravir and nirmatrelvir inhibits SARS-CoV-2 replication and shedding more effectively than individual treatments in the rhesus macaque model.

bioRxiv · Sep 3, 2022Microbiology

Molnupiravir (MK-4482) is efficacious against Omicron and other SARS-CoV-2 variants in the Syrian hamster COVID-19 model

K. Rosenke, A. Okumura, M. C. Lewis, F. Feldmann, K. Meade-White, W. F. Bohler, A. Griffin, R. Rosenke, C. Shaia, M. Jarvis, H. Feldmann

MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern, including Omicron, in the Syrian hamster model.

bioRxiv · Feb 22, 2022 · PreprintMicrobiology