Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack
J. M. van Rijn, A. C. C. Lopes, M. Ceylan, J. Eriksson, A. Bergholtz, A. Ntokaki, R. Hammar, M. Sundbom, M. Skogar, W. Graf, D.-L. Webb, P. M. Hellström, P. Artursson, T. Pelaseyed, M. L. Di Martino, M. E. Sellin
This study shows that maturation of human intestinal epithelial cells reduces susceptibility to Salmonella invasion by altering actin regulation, mucin expression, and glycocalyx composition.
bioRxiv · Jul 11, 2024Cell Biology