Author

M. Bosse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1 Evolutionary Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

M. Angelo· 4 shared S. C. Bendall· 4 shared N. F. Greenwald· 2 shared A. Baranski· 1 shared A. Bushuev· 1 shared A. Charmantier· 1 shared A. Delmastro· 1 shared A. E. Herr· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersImmunology

M. Angelo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics

M. L. Robinson, D. R. Glass, V. Duran, O. Rojas, A. M. Sanz, M. Consuegra, M. K. Sahoo, F. Hartmann, M. Bosse, R. M. G. Ramirez, N. Bueno, B. A. Pinsky, J. G. Montoya, H. Maecker, M. Cardenas, , S. Einav

The paper uses single-cell proteomics to analyze immune cell responses in severe dengue patients, identifying distinct immune dynamics compared to uncomplicated dengue.

bioRxiv · Sep 21, 2022Immunology

Reproducible, high-dimensional imaging in archival human tissue by Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)

C. C. Liu, M. Bosse, A. Kong, A. Kagel, R. Kinders, S. M. Hewitt, S. C. Bendall, M. Angelo

This study validates MIBI-TOF for consistent, high-dimensional imaging in archival human tissue, showing high concordance with single-plex IHC and automated cell population analysis.

bioRxiv · Oct 14, 2021Pathology

Virus-Dependent Immune Conditioning of Tissue Microenvironments

S. Jiang, C. N. Chan, X. Rovira-Clave, H. Chen, Y. Bai, B. Zhu, E. McCaffrey, N. F. Greenwald, C. Liu, G. L. Barlow, J. L. Weirather, K. Busman-Sahay, M. Nekorchuk, M. Terry, S. Younger, , G. P. Nolan

The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.

bioRxiv · May 21, 2021Immunology

Multiplexed Ion Beam Imaging Readout of Single-Cell Immunoblotting

G. Lomeli, M. Bosse, S. C. Bendall, M. Angelo, A. E. Herr

This paper introduces scIB-MIBI-TOF, a method combining single-cell immunoblotting with multiplexed ion beam imaging to detect proteoforms from glioblastoma cells.

bioRxiv · Mar 6, 2021Bioengineering

The great tit HapMap project: a continental-scale analysis of genomic variation in a songbird

L. G. Spurgin, M. Bosse, F. Adriaensen, T. Albayrak, C. Barboutis, E. Belda, A. Bushuev, J. Cecere, A. Charmantier, M. Cichon, N. J. Dingemanse, B. Doligez, T. Eeva, K. E. Erikstad, V. Federov, , Sheld

This study analyzes genomic variation across 647 great tit individuals to understand how environmental and demographic factors shape genetic diversity and differentiation.

bioRxiv · Dec 9, 2020Evolutionary Biology

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

E. F. McCaffrey, M. Donato, L. Keren, Z. Chen, M. Fitzpatrick, V. Jojic, A. Delmastro, N. F. Greenwald, A. Baranski, W. Graf, M. Bosse, P. K. Ramdial, E. Forgo, D. Van Valen, M. van de Rijn, , M. Angelo

This study uses multiplexed imaging and transcriptomics to identify immunosuppressive features in TB granulomas and blood, linking local and systemic immune responses.

bioRxiv · Jun 8, 2020 · PreprintImmunology