Author

W. H. Hildebrand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

D. A. Lewinsohn· 2 shared D. M. Lewinsohn· 2 shared E. J. Adams· 2 shared G. M. Swarbrick· 2 shared J. R. Krawic· 2 shared M. Cansler· 2 shared M. Null· 2 shared N. A. Ladd· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

D. A. Lewinsohn

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Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivJul 11, 2022

Delivery of loaded MR1 Monomer Results in Efficient Ligand Exchange to Host MR1 and Subsequent MR1T cell activation

C. A. Kulicke, G. M. Swarbrick, N. A. Ladd…·M. J. Harriff

The paper demonstrates that delivering MR1 monomers loaded with 5-OP-RU enables ligand exchange to host MR1, leading to MR1T cell activation.

DOI 10.1038/s42003-024-05912-4

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

ImmunologybioRxivMay 11, 2022

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

H. Jin, N. A. Ladd, A. M. Peev…·M. Harriff

This study modifies MR1 ligands to assess their impact on MR1-restricted T cell activation, revealing variable IFN-gamma responses and structural dynamics influencing recognition.

DOI 10.1038/s41598-022-26259-y

mechanistic / dynamical modelhost-pathogen & immune response

𝕏 PostBluesky

Cell BiologybioRxivPreprintOct 2, 2020

ScRNA-seq reveals tumor microenvironment remodeling induced by local intervention-based immunotherapy

A. R. Hoover, K. Liu, C. I. Devette…·W. R. Chen

This study uses scRNA-seq to show that LIT induces proinflammatory cytokine signaling and immune cell activation in tumor microenvironments of MMTV-PyMT mice.

DOI 10.1101/2020.10.02.323006

𝕏 PostBluesky