Author

W. P. D. Hendricks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:whole-exome sequencing· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. Sivaprakasam· 3 shared V. Zismann· 3 shared A. Sekulic· 2 shared C. Khanna· 2 shared J. Kiefer· 2 shared J. M. Trent· 2 shared J. Trent· 2 shared M. Murtaza· 2 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

K. Sivaprakasam

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4 papers

Recent·Most cited

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

S. Wong, E. Ehrhart, S. Stewart, V. Zismann, J. Cawley, R. Halperin, N. Briones, K. Richter, K. Sivaprakasam, N. Perdigones, T. Contente-Cuomo, S. Facista, J. M. Trent, M. Murtaza, C. Khanna, W. P. D. Hendricks

This study examines genomic heterogeneity in canine splenic hemangiosarcoma, identifying driver mutations and intratumoral diversity across multiple regions.

bioRxiv · Nov 15, 2020Cancer Biology

Identification of frequent activating HER2 mutations in primary canine pulmonary adenocarcinoma

G. Lorch, K. Sivaprakasam, V. Zismann, N. Perdigones, T. Contente-Cuomo, A. Nazareno, S. Facista, S. Wong, K. Drenner, W. S. Liang, J. M. Amann, S. L. Sinicropi-Yao, M. J. Koenig, K. La Perle, T. G. Whitsett, , W. P. D. Hendricks

This study identifies HER2 mutations in canine pulmonary adenocarcinomas, finding V659E mutations in 38% of cases and their association with drug sensitivity.

bioRxiv · Feb 25, 2019 · PreprintCancer Biology

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine melanoma by integrated comparative genomic analysis

W. P. D. Hendricks, V. Zismann, K. Sivaprakasam, C. Legendre, K. Poorman, W. Tembe, J. Kiefer, W. Liang, V. DeLuca, M. Stark, A. Ruhe, R. Froman, N. Duesbury, M. Washington, J. Aldrich, , J. Trent

This study identifies somatic PTPRJ mutations and dysregulated pathways in canine melanoma through genomic analysis, revealing similarities with human melanoma subtypes and potential therapeutic targets.

bioRxiv · Sep 30, 2017Cancer Biology

Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition

J. D. Lang, W. P. D. Hendricks, H. Yin, J. Kiefer, P. Ramos, R. Sharma, P. Pirrotte, E. A. Raupach, C. Sereduk, N. Tang, W. S. Liang, M. Washington, S. J. Facista, V. L. Zismann, E. M. Cousins, , J. M. Trent

This paper identifies ponatinib as a potent treatment for SCCOHT by inhibiting multiple kinases in preclinical models.

bioRxiv · Jul 6, 2017Cancer Biology