Author

W. S. Fisher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. R. Safinya· 2 shared K. K. Ewert· 2 shared V. M. Steffes· 2 shared L. Simon-Gracia· 1 shared P. D. Scodeller· 1 shared T. Teesalu· 1 shared V. Sidorenko· 1 shared Y. Li· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

C. R. Safinya

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Paclitaxel-loaded Cationic Fluid Lipid Nanodiscs and Liposomes with Brush-Conformation PEG Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation

L. Simon-Gracia, P. D. Scodeller, W. S. Fisher, V. Sidorenko, V. M. Steffes, K. K. Ewert, C. R. Safinya, T. Teesalu

This study shows that increasing PEG coverage on cationic lipid nanoparticles improves their tumor penetration and proapoptotic activity when delivering paclitaxel.

bioRxiv · Mar 28, 2022Biophysics

Enhanced Loading of Paclitaxel in Cationic Liposomes by Replacement of Oleoyl with Linoleoyl Lipid Tails with Benefits in Cancer Therapeutics from In Vitro Studies

Y. Zhen, K. K. Ewert, W. S. Fisher, V. M. Steffes, Y. Li, C. R. Safinya

This study shows that replacing oleoyl with linoleoyl lipid tails in cationic liposomes increases paclitaxel solubility, enhancing cancer therapeutic efficacy without increasing toxicity.

bioRxiv · Oct 12, 2020Biophysics