Author

Wenzhen Zhu

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ali NajiiD· 1 shared Anna Chiara RussoiD· 1 shared Brent Pederson· 1 shared Brigid Ellen GreggiD· 1 shared Chengyang LiuiD· 1 shared Darleen A. SandovaliD· 1 shared Hannah HafneriD· 1 shared Iris LindbergiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ali NajiORCID

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1 paper

Recent·Most cited

SEL1L-HRD1 ER-Associated Degradation Facilitates Prohormone Convertase 2 Maturation and Glucagon Production in Islet α Cells

Wenzhen Zhu, Linxiu Pan, Xianwei Cui, Anna Chiara Russo, ROHIT RAY, Brent Pederson, Xiaoqiong Wei, Liangguang Leo Lin, Mauricio Torres, Hannah Hafner, Brigid Ellen Gregg, Neha Shrestha, Chengyang Liu, Ali Naji, Peter R. Arvan, , Rachel B. Reinert

This study identifies SEL1L-HRD1 ERAD as a regulator of PC2 maturation and glucagon production in islet α cells by degrading misfolded proPC2.

Nature Communications · Feb 25, 2026Peer-reviewedCell Biology