Author

Brigid Ellen Gregg

University of MichiganORCID 0000-0002-1192-2997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ali NajiiD· 1 shared Anna Chiara RussoiD· 1 shared Brent Pederson· 1 shared Chengyang LiuiD· 1 shared Darleen A. SandovaliD· 1 shared Dave BridgesiD· 1 shared Haijing SuniD· 1 shared Hannah HafneriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Ali NajiORCID

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2 papers

Recent·Most cited

SEL1L-HRD1 ER-Associated Degradation Facilitates Prohormone Convertase 2 Maturation and Glucagon Production in Islet α Cells

Wenzhen Zhu, Linxiu Pan, Xianwei Cui, Anna Chiara Russo, ROHIT RAY, Brent Pederson, Xiaoqiong Wei, Liangguang Leo Lin, Mauricio Torres, Hannah Hafner, Brigid Ellen Gregg, Neha Shrestha, Chengyang Liu, Ali Naji, Peter R. Arvan, , Rachel B. Reinert

This study identifies SEL1L-HRD1 ERAD as a regulator of PC2 maturation and glucagon production in islet α cells by degrading misfolded proPC2.

Nature Communications · Feb 25, 2026Peer-reviewedCell Biology

GDF15 knockout does not substantially impact perinatal body weight or neonatal outcomes in mice

Molly C. Mulcahy, Noura El Habbal, JeAnna R. Redd, Haijing Sun, Brigid Ellen Gregg, Dave Bridges

This study examines the role of GDF15 in pregnancy and neonatal outcomes using a knockout mouse model, finding no major effects on body weight or survival.

Endocrinology · Oct 22, 2024Peer-reviewedPhysiology