X. Dong

This paper determines the structural basis of how Rpn13 recognizes K48-linked Ub chains through a bivalent interaction, revealing a mechanism for proteasomal selectivity.

This study investigates microbial energy and carbon acquisition strategies in deep-sea petroleum seeps using metagenomic analysis and geochemical data.

The paper identifies BAP1 loss as a marker for a distinct immunogenic PeM subtype, suggesting potential therapeutic targets like immune checkpoint inhibitors.

This study identifies a deletion in TMPRSS6 associated with reduced hemoglobin and improved blood viscosity in Tibetan pigs adapted to high altitude.

This study characterizes the structure, function, and dynamics of the gamete fusogen HAP2, revealing dynamic regions and structural features critical for fusion.

This paper introduces a metaproteomics method called direct Protein-SIF and software to measure carbon isotope ratios in microbial communities, confirming its accuracy and utility in studying microbial metabolism.

The paper determines the structure of pro-TGF-β1 with a cleavage site mutation, revealing prodomain-GF domain swapping in the dimeric structure and its implications for TGF-β biosynthesis.

The paper develops metaproteomics methods to assess microbial community composition by measuring biomass contributions through protein abundance, validated using artificial communities and applied to environmental and saliva samples.