X. Dong

This study examines how temperature affects the behavior and molecular responses of Neptunea cumingii, showing significant physiological and transcriptomic changes outside the optimal temperature range of 8–16°C.

This study identifies AGL16's role in regulating gene expression and flowering time in Arabidopsis, showing partial dependency on SOC1 and involvement in water loss and seed dormancy.

This study identifies novel SARS-CoV-2 receptors through a CRISPR activation screen, revealing LDLRAD3, TMEM30A, and CLEC4G as functional receptors independent of ACE2.

This study identifies dipeptides as minimalistic yet sufficient for liquid-liquid phase separation through computational and experimental methods.

The paper analyzes SARS-CoV-2 sequence variation in patient samples and compares the in vitro growth of B.1.1.7 and B.1.351 variants to other isolates, finding no significant difference in growth for B.1.1.7.

This paper develops a circular RNA vaccine encoding SARS-CoV-2 Spike RBD, showing broad protection against multiple variants including Delta and Omicron.

This study identifies 24 FDA-approved compounds that inhibit SARS-CoV-2 replication, with five showing high safety indices and blocking S protein-mediated cell fusion.

The paper analyzes public data to show that PDCD1 and CD274 expression in T cells and macrophages correlates with COVID-19 severity.

This study introduces a fast lysine cross-linker DOPA for mass spectrometry analyses, showing it enables rapid protein cross-linking and captures dynamic conformational changes and weak protein-protein interactions.

This study shows allantoin induces pruritus in CKD by activating MrgprD and TRPV1 in DRG neurons.

This study shows that sequential infection with influenza A virus followed by SARS-CoV-2 in mice leads to more severe disease and encephalitis compared to single infections.

The paper analyzes viral diversity in deep sea cold seep sediments, finding high endemism and links to microbial hosts and biogeochemical cycling.

The paper identifies humoral immune responses to SARS-CoV-2 and other human coronaviruses peptides to detect infections and discover immunity biomarkers.

This study examines the relationship between motor fitness, fundamental movement skills, and functional movement screen in primary school children, finding weak correlations and suggesting independent systems in motor development.

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

The paper examines how PD-L1 expression on tumor cells affects specific cell clusters in TCR-T cells through single-cell RNA sequencing and cytotoxicity assays.

This study shows that bacterial outer membrane vesicles from pathogenic and beneficial Pseudomonas species activate plant immune responses, offering protection against pathogens and revealing distinct mechanisms of action.

The paper assesses how tumor PD-L1 levels impact TCR-T cell function and anti-PD-(L)1 efficacy using single-cell RNA sequencing and cellular assays.

The paper identifies genetic elements and QTL associated with stem prickle development in roses, linking prickle density to water-related adaptations.

The paper introduces ctmmweb, a graphical interface for autocorrelation-informed home range estimation, demonstrating its use on jaguar tracking data.

The paper shows mitochondria form contact sites with the nucleus to facilitate a pro-survival retrograde response by stabilizing transcription factors like NF-kB.

This study profiles microbial activities in deep sea cold seep sediments, revealing hydrocarbon oxidation pathways and their role in sustaining diverse microbial communities across redox gradients.

This study examines microbiome changes in lung and gut of NSCLC patients and finds sputum microbiota better predicts disease and metastasis than gut microbiota, with machine learning models achieving 0.842 AUC.

The paper identifies CsHscB from Clonorchis sinensis as a TLR2 agonist that modulates macrophage activation and IL-10 production through TLR2-dependent mechanisms.

This paper identifies aCPSF1 as the first general transcription termination factor in Archaea, revealing its cleavage-dependent termination mechanism and evolutionary relationship to eukaryotic processes.

The paper predicts and validates common neoantigens in colorectal cancer that are both presented and immunogenic, identifying potential universal targets for immunotherapy.

This study uses genome-wide sequence data to reconstruct the phylogeny of diploid wheat wild relatives and identifies recurrent hybridization events shaping their evolution.

The paper develops a high-content Virion Display (VirD) array of human GPCRs to profile their biochemical activities and identifies potential drug targets.

The paper identifies a shared core microbiome across distant soda lakes and suggests common design principles for high productivity.