Author

X. Schafer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1

Frequent Co-Authors

J. Munger· 3 shared I. Rodriguez-Sanchez· 2 shared I. Moreno· 1 shared I. S. Harris· 1 shared J. Zhang· 1 shared K. Nehrke· 1 shared K. Welle· 1 shared L. Smorodintsev-Schiller· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

J. Munger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose limitation

M. H. Raymonda, I. Rodriguez-Sanchez, X. Schafer, L. Smorodintsev-Schiller, I. S. Harris, J. Munger

This paper shows that HCMV's UL38 protein inactivates TSC2, disrupting glucose-fatty acid biosynthesis coupling and making cells vulnerable to glucose limitation.

bioRxiv · May 17, 2023 · PreprintMicrobiology

Human Cytomegalovirus induces neuronal enolase to support virally-mediated metabolicremodeling

I. Moreno, I. Rodriguez-Sanchez, X. Schafer, J. Munger

This study identifies ENO2 as a key metabolic enzyme induced by HCMV to support glycolysis and UDP-sugar metabolism, essential for viral glycoprotein production and infectivity.

bioRxiv · Apr 26, 2022Microbiology

Potential Mechanisms Linking SIRT Activity And Hypoxic 2-Hydroxyglutarate Generation: No Role For Direct Enzyme (De)acetylation

S. Nadtochiy, Y. T. Wang, J. Zhang, K. Nehrke, X. Schafer, K. Welle, S. Ghaemmaghami, J. Munger, P. Brookes

This study investigates whether sirtuin-mediated acetylation regulates 2-HG production by metabolic enzymes, finding no direct link between enzyme acetylation and 2-HG generation.

bioRxiv · May 24, 2017Biochemistry