Author

Xuefei Chen

Michael G. DeGroote Institute for Infectious Disease ResearchPrimary ORCID profile (0009-0006-6304-5777 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Xuefei CheniD1 paper · University of Oxford

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aline Fiebig‐ComyniD· 1 shared Allison K. GuitoriD· 1 shared Amelia Bing Ya Guo· 1 shared Anna Floyd AveretteiD· 1 shared Bonnie YiuiD· 1 shared Brian K. CoombesiD· 1 shared Emily PuumalaiD· 1 shared Eric D. BrowniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aline Fiebig‐ComynORCID

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1 paper

Recent·Most cited

Butyrolactol A potentiates caspofungin efficacy against resistant fungi via phospholipid flippase inhibition

Xuefei Chen, H. Diessel Duan, Michael J. Hoy, Kalinka K. Koteva, Michaela Spitzer, Allison K. Guitor, Emily Puumala, Aline Fiebig‐Comyn, Guanggan Hu, Bonnie Yiu, Sommer Chou, Zhuyun Bian, Yeseul Choi, Amelia Bing Ya Guo, Wenliang Wang, , Gerard D. Wright

The paper identifies butyrolactol A as a compound that enhances caspofungin efficacy against resistant fungi by inhibiting phospholipid flippase, thereby improving antifungal treatment.

Cell · Dec 31, 2025Peer-reviewedBiochemistry