Guanggan Hu

The paper identifies butyrolactol A as a compound that enhances caspofungin efficacy against resistant fungi by inhibiting phospholipid flippase, thereby improving antifungal treatment.

This study shows that polyphosphate mobilization is critical for Cryptococcus neoformans virulence in a mouse model, affecting cell surface structure, immune response, and mitochondrial function.

This study shows that glutathione metabolism in Cryptococcus neoformans affects virulence by modulating redox processes and melanin production in a murine infection model.

This paper investigates how mitochondrial electron transport chain function and iron regulatory factors influence melanin formation in Cryptococcus neoformans, revealing a link between mitochondrial dysfunction, redox homeostasis, and virulence.