Y. Dong

This study shows that andrographolide reduces NAFLD in HFD-fed ApoE(-/-) mice by modulating gut microbiota and inhibiting inflammation pathways.

This study reports the crystal structure of the N-terminal domain of DdMCU and shows its oligomeric state and calcium-dependent dissociation.

This study shows CD44 deficiency in mice leads to impaired alveolar macrophage lipid homeostasis, increased surfactant lipids, and exacerbated lung inflammation.

This study demonstrates that transient expression of Runx1 and Hoxa9 in pluripotent stem cells generates functional T cells capable of immune surveillance and tumor eradication.

This study shows N-acetyl cysteine (NAC) alleviates Coxsackievirus B-induced myocarditis by inhibiting caspase-1 and viral proteases, offering a potential therapeutic option.

This study presents cryo-EM structures of the human glutamine transporter SLC1A5 in an outward-facing conformation, revealing insights into its transport mechanism and substrate recognition.

This paper identifies MraW as a DNA methylase in E. coli O157:H7, showing its role in motility, colonization, and virulence through genome-wide methylation and regulation of flagellar genes.

The paper identifies FTL9 as a gene required for short-day vernalization in Brachypodium distachyon, showing natural variation in this trait is due to allelic differences in FTL9.

The paper presents cryo-EM structures of the human 26S proteasome in seven conformational states during polyubiquitylated protein degradation, revealing dynamic substrate-proteasome interactions and ATP hydrolysis mechanisms.

This study identifies and characterizes WRKY genes in melon, analyzes their evolution, and assesses their role in powdery mildew resistance.

The paper uses plaque-MSI to reveal a metabolic shift towards odd-chain fatty acid lipids during host-virus interactions in Emiliania huxleyi.

The paper identifies TCF21-Slug interactions that define phenotypic plasticity and sub-classes in high-grade serous ovarian cancer.

The paper identifies 5hmC signatures in cfDNA as accurate biomarkers for detecting colorectal and gastric cancers, outperforming conventional markers and matching tissue biopsy results.