Author

Y. Kipnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. K. Bera· 2 shared D. Baker· 2 shared A. Chang· 1 shared A. Fernandez· 1 shared A. Kang· 1 shared A. Olshefsky· 1 shared A. Roy· 1 shared B. I. M. Wicky· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

A. K. Bera

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Author profile →

2 papers

Recent·Most cited

Improving protein expression, stability, and function with ProteinMPNN

K. H. Sumida, R. Nunez Franco, I. Kalvet, S. J. Pellock, B. I. M. Wicky, L. F. Milles, J. Dauparas, J. Wang, Y. Kipnis, N. Jameson, A. Kang, J. De La Cruz, B. Sankaran, A. K. Bera, G. Jimenez Oses, D. Baker

This paper introduces ProteinMPNN, a deep learning model that improves protein expression, stability, and function by incorporating evolutionary and structural information.

bioRxiv · Oct 3, 2023Biochemistry

De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8

A. Roy, L. Shi, A. Chang, X. Dong, A. Fernandez, J. C. Kraft, J. Li, V. Q. Le, R. V. Winegar, G. M. Cherf, D. Slocum, P. D. Poulson, G. E. casper, M. L. Vallecillo-Zuniga, J. C. Valdoz, , D. Baker

This paper designs highly selective miniprotein inhibitors for integrins αvβ6 and αvβ8 with picomolar affinity and therapeutic potential in a mouse fibrosis model.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry