Y. Wu

This paper introduces a method combining instant structured illumination microscopy with TIRF to achieve higher resolution and faster imaging of live samples near the coverslip.

This study presents a method for 3D morphological reconstruction and force inference in early C. elegans embryos, showing deviations of 7% and 10% from force balance and Young-Laplace relations.

This paper introduces a reflective imaging technique that enhances resolution, speed, and collection efficiency in light sheet microscopy without altering the microscope hardware.

The paper identifies Boi1p and Boi2p as essential proteins that mediate vesicle fusion and Cdc42p activation during yeast polar growth.

The paper demonstrates that membrane tension-sensitive calcium currents and ion channels regulate Rho GTPase and myosin contraction, and that YAP translocates in response to mechanical compression.

This paper develops a CRISPRi library for high-throughput functional genomics in E. coli, identifies sgRNA design rules, and validates gene-phenotype associations with high specificity.