Author

Y.-H. Tu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Organism:chicken / avian· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

A. B. Ward· 2 shared B. Teng· 2 shared B. Burendei· 1 shared C. C. Tsui· 1 shared C.-L. Hsu· 1 shared C.-Y. Lin· 1 shared D. Xu· 1 shared D.-D. Zou· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

A. B. Ward

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-cell Sequencing Highlights Heterogeneity and Malignant Progression in Actinic Keratosis and Cutaneous Squamous Cell Carcinoma

D.-D. Zou, Y.-Z. Sun, X.-J. Li, W.-J. Wu, D. Xu, Y.-T. He, J. Qi, Y. Tu, Y. Tang, Y.-H. Tu, X.-L. Wang, X. Li, F.-Y. Lu, L. Huang, H. Long, , X. Li

This study uses single-cell RNA-seq to analyze the progression from actinic keratosis to cutaneous squamous cell carcinoma, identifying key driver genes and tumor microenvironment interactions.

eLife · Dec 15, 2023Peer-reviewedCancer Biology

Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels

B. Teng, J. Kaplan, Z. Liang, Z. Krieger, Y.-H. Tu, B. Burendei, A. B. Ward, E. Liman

This study identifies structural motifs in OTOP channels that determine subtype-specific pH sensitivity, showing that proton gating is mediated by extracellular linkers in the N and C domains.

bioRxiv · Mar 1, 2022Biophysics

Thymic macrophages consist of two populations with distinct localization and origin

T.-A. Zhou, H.-P. Hsu, Y.-H. Tu, H.-K. Cheng, C.-Y. Lin, N.-J. Chen, J.-W. Tsai, E. A. Robey, H.-C. Huang, C.-L. Hsu, I. L. Dzhagalov

This study identifies two distinct thymic macrophage populations with different locations and origins using single-cell RNA sequencing and genetic fate mapping.

bioRxiv · Nov 4, 2021Immunology

Structures of the Otopetrin Proton Channels Otop1 and Otop3

K. Saotome, B. Teng, C. C. Tsui, W.-H. Lee, Y.-H. Tu, M. S. P. Sansom, E. R. Liman, A. B. Ward

The paper reports cryo-EM structures of zebrafish Otop1 and chicken Otop3, revealing their dimeric architecture and potential proton conduction pathways.

bioRxiv · Feb 6, 2019Biochemistry