Tabiwang N. Arrey

This paper introduces a high-resolution multi-pass Astral analyzer mode for TMT proteomics, enabling 35-plex quantification with improved depth and precision.

Orbitrap Astral Zoom upgrades enable 270 Hz DIA scanning, identifying 7184 protein groups at 500 samples/day and >12,000 proteins from fractionated HEK293 in 2.7 h.

This paper introduces a single-aliquot, enrichment-free workflow for high-throughput plasma proteome and N-glycoproteome profiling, achieving deep coverage and reproducibility in a clinical setting.

This paper develops a high-sensitivity single-cell proteomics platform and applies it to analyze small immune cells, achieving deep proteome coverage and identifying key markers in PBMCs.

The paper introduces iDIA, a method that enhances sensitivity for quantifying regulatory proteins in single cells, revealing lineage priming and cell-cycle coordination in hematopoietic stem and progenitor cells.

This study evaluates the Orbitrap Astral MS's sensitivity for single-cell proteomics, showing improved proteome coverage and quantitative accuracy in low-input samples.

This paper introduces a high-throughput single-cell proteomics workflow achieving 5300 protein groups per cell with high accuracy, enabling the study of cellular heterogeneity and lineage differentiation.

This paper introduces TEAQ, a software tool that selects clinical-grade biomarker candidates from DIA-MS data by evaluating protein quantification metrics in a discovery cohort.

The paper introduces a method using the Orbitrap Astral mass spectrometer with DIA to rapidly analyze phosphoproteomes, detecting over 80,000 phosphorylation sites in mice.

This study evaluates the Astral mass analyzer's performance in single-cell proteomics using DIA, showing improved proteome depth and quantitative precision for ultra-low input samples.

The paper introduces Narrow-window DIA, a fast proteomics method enabling high-throughput and comprehensive proteome analysis with high precision and accuracy.