Author

Yanru Ji

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Chongli YuaniD· 2 shared Fei LiuiD· 2 shared Jean-Christophe RochetiD· 2 shared Ranjie XuiD· 2 shared Bryce David Colon· 1 shared Changlin WaniD· 1 shared Chao QiiD· 1 shared Connor Joseph Meek· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Chongli YuanORCID

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2 papers

Recent·Most cited

Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer's tau pathology and uncover human-specific neuronal vulnerability

Yanru Ji, Purba Mandal, Jiahui Liu, Wen Hu, Bryce David Colon, Changlin Wan, Raymond W. Pan, Dongkai Guo, Lijia Zhang, Xingjian Gu, Yang Yang, Kun Huang, Riyi Shi, Chao Qi, Chongli Yuan, , Ranjie Xu

This study develops a human neuronal chimera model to study Alzheimer's tau pathology, showing human-specific vulnerability and recapitulating mature AD features in vivo.

bioRxiv · Jul 9, 2026 · PreprintNeuroscience

Alzheimer's Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery

Yanru Ji, Xiaoling Chen, Zhen Wang, Connor Joseph Meek, Jenna Lillie McLean, Yang Yang, Chongli Yuan, Jean‐Christophe Rochet, Fei Liu, Ranjie Xu

This study uses vascularized neuroimmune organoids to model sporadic Alzheimer's disease and test drug efficacy.

Molecular Psychiatry · May 2, 2025Peer-reviewedNeuroscience