Author

Yi Han

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adam C. EnglishiD· 1 shared Aishwarya PisupatiiD· 1 shared Alexey I. NesvizhskiiiD· 1 shared Alice M. Sanchez· 1 shared All of Us Research Program Long-Read Working Group· 1 shared Andrei I. IvanoviD· 1 shared Ben C. CollinsiD· 1 shared Benjamin Myers· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperGenetics

Adam C. EnglishORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic and Epigenetic Landscape of Self-Identified Hispanics/Latino in All Of Us

Adam C. English, Yilei Fu, Luis F. Paulin, Michal B. Izydorczyk, Sairam Behera, Qiuhui Li, Xinchang Zheng, Yiming Zhu, Justin Paschall, Grace E. Tietz, Jessica Honorato-Mauer, Luke B. Morina, Sean Griffith, Aishwarya Pisupati, Siyu Wang, , Fritz J. Sedlazeck

The paper analyzes genetic variation, ancestry, and DNA methylation in Hispanic/Latino participants using long-read sequencing, identifying novel variants and phenotype associations.

bioRxiv · Nov 2, 2026 · PreprintGenetics

Spatial distribution of the proteome in human body and cancers

Liang Yue, Wenhao Jiang, Sainan Li, Meng Luo, Ning Fan, Xiaolu Zhan, Rui Sun, Honghan Cheng, Zhangzhi Xue, Tong Liu, Qianhe Zhou, Kexin Chen, Tian Lu, Fang Guo, Dongwei Li, , Tiannan Guo

The paper presents a comprehensive spatial proteome map of human tissues and cancers, enabling drug response analysis and target discovery.

Nature · Jun 17, 2026Peer-reviewedSystems Biology

Intestinal stem cells enhance local mucosal immunity through apoptotic body phagocytosis

Julie Y. Zhou, Qiuhe Lu, Yujia Hu, Satoru Fujii, Scott T. Espenschied, Morgan J. Engelhart, Kelsey J. Lewis, Paul E. Karell, Yi Han, Heaji Shin, Robert E. Schmidt, Daniel J. Silver, Andrei I. Ivanov, Ömer H. Yilmaz, Thaddeus S. Stappenbeck

This study shows that intestinal stem cells (ISCs) enhance local mucosal immunity by engulfing apoptotic bodies, which leads to increased T cell activity through TNF signaling.

bioRxiv · Oct 29, 2024 · PreprintCell Biology