Yong Wang

Simultaneous Functional Ultrasound, Intrinsic Optical Signal and Widefield Calcium Neuroimaging

This study combines functional ultrasound with optical imaging to show CBV correlates with hemoglobin and calcium activity in awake mice, and applies it to study neurovascular dysfunction in glioblastoma.

TAR syndrome causal gene RBM8A is critical for embryonic bone development and proper Hedgehog signaling

This study shows that RBM8A is essential for bone development and Hedgehog signaling, with its deficiency causing skeletal defects and impaired endochondral ossification.

Hyaluronic Acid-Modified Mesoporous Manganese Dioxide Combined with Carboplatin Synergistically Enhances Ovarian Cancer Therapy

This study develops CBP@HMnO2@HA nanoparticles that combine chemotherapy and chemodynamic therapy, enhancing ovarian cancer treatment by inducing immunogenic cell death and targeting tumors.

Reusing wasted bioresources for crop protection: Calcinated oyster shell powder enhances rhizospheric microbial-mediated suppression of root-knot nematodes

This study shows that calcinated oyster shell powder suppresses root-knot nematodes by inhibiting their migration and enhancing microbial suppression in the rhizosphere.

The Arabidopsis 14-3-3 proteins stabilize BRASSINOSTEROID INSENSITIVE1 at the plasma membrane

This study identifies 14-3-3 proteins as stabilizers of BRI1 by antagonizing its ubiquitination, enhancing BR signaling in Arabidopsis.

Endothelial cannabinoid CB1 receptor deficiency reduces arterial inflammation and lipid uptake in response to atheroprone shear stress

This paper shows that blocking endothelial CB1 receptors reduces arterial inflammation and lipid uptake under atheroprone shear stress, suggesting potential therapeutic benefits for atherosclerosis.

Biased Auditory Nerve Central Synaptopathy Exacerbates Age-related Hearing Loss

The paper investigates how different types of spiral ganglion neuron synapses in the cochlear nucleus change during age-related hearing loss, finding that non-calretinin-expressing synapses degenerate more severely.

Characterization of Isoforms of the Ovine Granulocyte Colony Stimulating Factor

This study compares two ovine GCSF variants, finding that GCSFv2 has higher activity and mRNA expression than GCSFv1, and that the C-terminal region is most effective in promoting neutrophil maturation and progenitor cell functions.

Verify Hub Genes of expression profile in aortic dissection

The paper identifies hub genes and molecular pathways associated with thoracic aortic dissection using microarray analysis and bioinformatics.

HIV protease inhibitor Saquinavir inhibits toll-like receptor 4 activation by targeting receptor dimerization

This study shows that Saquinavir inhibits both MyD88- and TRIF-dependent TLR4 signaling pathways by blocking receptor dimerization, suggesting it targets the TLR4 receptor complex.

Robust nonparametric descriptors for clustering quantification in single-molecule localization microscopy

This paper introduces a nonparametric descriptor, J'(r), to quantify clustering in single-molecule localization microscopy by analyzing nearest neighbor distribution functions.