Author

Yumei Li

University of California, Irvine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:GWAS / association mapping· 2 Assay:scRNA-seq· 2 Assay:snRNA-seq· 2

Frequent Co-Authors

Rui CheniD· 3 shared Han CheniD· 2 shared Ismail Yaman· 2 shared J. Timothy Stout· 2 shared Jean LiiD· 2 shared Jianming ShaoiD· 2 shared Jie ZhengiD· 2 shared Jinjing JianiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Rui ChenORCID

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Author profile →

4 papers

Recent·Most cited

An Integrated Multi-omics Single Cell Atlas of the Human RPE and Choroid

Jianming Shao, Xuan Bao, Ismail Yaman, Y Zheng, Jun Wang, Jin Li, Tingting Yang, Jinjing Jian, Jean Li, Seth Blackshaw, Kapil Bharti, Margo S. Clarke, Dwight E. Stambolian, C Sung, Jie Zheng, , Rui Chen

The paper constructs a multi-omics single-cell atlas of human RPE and choroid, identifying cell types, aging patterns, and genetic risk factors for AMD.

bioRxiv · Jul 24, 2026 · PreprintGenomics

An Integrated muti-omics cell atlas of the human trabecular meshwork and ciliary body

Jinjing Jian, Xuan Bao, Jun Wang, Y Zheng, Jin Li, Jianming Shao, Tingting Yang, Ismail Yaman, Jean Li, Han Chen, Nicholas G. Tolman, Richard H. Scheuermann, Jie Zheng, Carl Sheridan, Yutao Liu, , Rui Chen

The paper creates a multi-omics atlas of human trabecular meshwork and ciliary body cells, identifying cell types and regulatory programs linked to glaucoma.

bioRxiv · Jun 22, 2026 · PreprintGenomics

Systemic interindividual epigenetic variants link periconceptional environment to human fetal development

Chathura Gunasekara, Wen-Jou Chang, Maria S. Baker, Prachand Issarapu, Goo Jun, Garrett Hellenthal, Matt J. Silver, Andrew M. Prentice, Cristian Coarfa, Yumei Li, Rui Chen, Robert A. Waterland

The paper identifies systemic epigenetic variants linked to periconceptional environments in human fetal development, finding more variants in Black Americans and associations with cancer and neurodevelopment.

bioRxiv · Jun 16, 2026 · PreprintMolecular Biology

CSRefiner: A lightweight framework for fine-tuning cell segmentation models with small datasets

Can Shi, Yumei Li, Jing Guo, Qiuling Chen, Tingting Cao, Sha Liao, Ao Chen, Mei Li, Ying Zhang

CSRefiner improves cell segmentation accuracy with small datasets by fine-tuning existing models for spatial transcriptomics.

Briefings in Bioinformatics · Dec 22, 2025Peer-reviewedBioinformatics