Author

Z. Ivics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

C. Miskey· 5 shared D. Todt· 3 shared R. J. P. Brown· 3 shared A. Ebenig· 2 shared C. Goffinet· 2 shared S. Pfaender· 2 shared A. Auste· 1 shared A. Breithaupt· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

C. Miskey

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells

C. F. Magnani, R. Myburgh, S. Brunn, M. Chambovey, M. Ponzo, L. Volta, C. Pellegrino, S. Pascolo, C. Miskey, Z. Ivics, J. A. Shizuru, D. Neri, M. G. Manz

This study develops anti-CD117 CAR T cells with a safety switch to target and eliminate acute myeloid leukemia and hematopoietic stem cells in preclinical models.

bioRxiv · Jun 15, 2023Cancer Biology

SARS-CoV-2 entry route impacts a range of downstream viral and cellular processes

B. Qu, C. Miskey, A. Goemer, D. Potmus, M. Nocke, R. D. V. Kleinert, T. K. Itotia, L. Valder, J. Brueckmann, S. Hoeck, F. D. Hastert, C. von Rhein, C. Schuermann, A. Ebenig, M. Widera, , R. J. P. Brown

This study shows that SARS-CoV-2 entry via TMPRSS2 or endolysosomal cathepsins affects viral replication, immune response, and genome evolution.

bioRxiv · Aug 5, 2022 · PreprintMicrobiology

In contrast to TH2-biased approaches, TH1 COVID-19 vaccines protect Syrian hamsters from severe disease in the absence of dexamethasone-treatable vaccine-associated enhanced respiratory pathology

A. Ebenig, S. Muraleedharan, J. Kazmierski, D. Todt, A. Auste, M. Anzaghe, A. Gömer, D. Postmus, P. Gogesch, M. Niles, R. Plesker, C. Miskey, M. Gellhorn Serra, A. Breithaupt, C. Hörner, , M. D. Mühlebach

This study compares TH1 and TH2-biased vaccines in Syrian hamsters, showing that TH1 vaccines prevent severe disease without inducing VAERD, while TH2 vaccines cause VAERD through eosinophil recruitment and TH2 cytokine upregulation.

bioRxiv · Dec 28, 2021 · PreprintImmunology

Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements

B. Tegtmeyer, G. Vieyres, D. Todt, C. Lauber, C. Ginkel, M. Engelmann, M. Herrmann, C. K. Pfaller, F. W. R. Vondran, R. Broering, E. Vafadarnejad, A.-E. Saliba, C. Puff, W. Baumgärtner, C. Miskey, , R. J. P. Brown

This study identifies temporally structured transcriptional changes in HCV-infected human hepatocytes, revealing both antiviral and pro-viral programs that may contribute to viral persistence.

bioRxiv · Feb 12, 2021Immunology

Genomic Analyses of SLAMF7 CAR-T Cells Manufactured by Sleeping Beauty Transposon Gene Transfer for Immunotherapy of Multiple Myeloma

C. Miskey, M. Amberger, M. Reiser, S. Prommersberger, J. Beckmann, M. Machwirth, H. Einsele, M. Hudecek, H. Bonig, Z. Ivics

This paper characterizes the genomic safety of SLAMF7 CAR-T cells produced using Sleeping Beauty transposon technology for multiple myeloma treatment, showing safe integration and no residual transposase.

bioRxiv · Aug 27, 2019 · PreprintBioengineering