Author

Z. Izadifar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

D. E. Ingber· 3 shared A. Gulati· 2 shared E. Doherty· 2 shared G. Goyal· 2 shared N. T. LoGrande· 2 shared T. To· 2 shared V. Horvath· 2 shared A. Junaid· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBioengineering

D. E. Ingber

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

M. M. Sperry, B. Charrez, H. Fotowat, E. Gardner, K. Pilobello, Z. Izadifar, T. Lin, A. Kuelker, S. Kaki, M. Lewandowski, S. Lightbown, R. Martinez, S. Marquez, J. Moore, M. Plaza-Oliver, , D. E. Ingber

The paper identifies SNC80 as a drug that reversibly slows metabolism in Xenopus and demonstrates its cross-species applicability in human organs-on-chips and porcine organs.

eLife · Sep 24, 2024Peer-reviewedBioengineering

Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips

Z. Izadifar, J. Cotton, C. Chen, N. A. Bustos, V. Horvath, A. Stejskalova, C. Wu, A. Gulati, N. T. LoGrande, B. Budnik, S. Shahriar, E. Doherty, T. To, S. E. Gilpin, A. M. Sesay, , D. E. Ingber

This paper develops human cervical Organ Chip models to study mucus production, host-microbiome interactions, and immune responses, showing they mimic in vivo conditions and respond to microbiome changes.

bioRxiv · Feb 22, 2023 · PreprintBioengineering

Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip

G. Mahajan, E. Doherty, T. To, A. Sutherland, J. Grant, A. Junaid, A. Gulati, N. T. LoGrande, Z. Izadifar, S. S. Timilsina, V. Horvath, R. Plebani, M. France, I. Hood-Pishchany, S. Rakoff-Nahoum, , D. E. Ingber

This paper develops a human vagina-on-a-chip model to study vaginal microbiome-host interactions and their effects on health outcomes.

bioRxiv · Mar 20, 2022Microbiology

Induction of long-term allogeneic cell acceptance and formation of immune privileged tissue in immunocompetent Hosts

J. Harding, K. Vintersten-Nagy, M. Shutova, H. Yang, J. Tang, M. Massumi, M. Izadifar, Z. Izadifar, P. Zhang, C. Li, A. Nagy

This paper demonstrates that expressing eight immunomodulatory genes in mouse embryonic stem cells enables them to avoid immune rejection and form immune-privileged tissues in allogeneic hosts.

bioRxiv · Jul 30, 2019 · PreprintBioengineering