Author

Z. Kechagia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

A. E. M. Beedle· 2 shared I. Andreu· 2 shared P. Roca-Cusachs· 2 shared X. Trepat· 2 shared A. Elosegui-Artola· 1 shared A.-L. Le Roux· 1 shared B. Falcones· 1 shared I. Almendros· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

A. E. M. Beedle

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2 papers

Recent·Most cited

The laminin-keratin link shields the nucleus from mechanical deformation and signalling

Z. Kechagia, P. Saez, M. Gomez-Gonzalez, M. Zamarbide, I. Andreu, T. Koorman, A. E. M. Beedle, P. W. B. Derksen, X. Trepat, M. Arroyo, P. Roca-Cusachs

This study shows laminin-111 shields the nucleus from mechanical deformation by linking integrin {beta}4 to keratin, affecting YAP localization and chromatin methylation in breast epithelial cells.

bioRxiv · Mar 1, 2022Cell Biology

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

I. Andreu, B. Falcones, S. Hurst, N. Chahare, X. Quiroga, A.-L. Le Roux, Z. Kechagia, A. E. M. Beedle, A. Elosegui-Artola, X. Trepat, R. Farre, T. Betz, I. Almendros, P. Roca-Cusachs

This study shows that the rate of force application drives cell mechanosensing through reinforcement and fluidization mechanisms.

bioRxiv · Mar 8, 2021Biophysics