Author

T. Koorman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:plant (other)· 1

Frequent Co-Authors

P. W. B. Derksen· 2 shared A. E. M. Beedle· 1 shared A. J. E. Pelgrom· 1 shared B. T. Goult· 1 shared C.-N. Meisrimler· 1 shared C.-Y. Lee· 1 shared G. Van den Ackerveken· 1 shared I. Andreu· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

P. W. B. Derksen

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3 papers

Recent·Most cited

A novel cancer-associated cassette exon in TLN1 alters Talin 1 mechanosensitivity

L. M. Gallego-Paez, W. J. S. Edwards, Y. Guo, M. Chanduri, T. Koorman, C.-Y. Lee, N. Grexa, P. W. B. Derksen, J. Yan, M. A. Schwartz, J. Mauer, B. T. Goult

The paper identifies a cancer-associated exon in TLN1 that alters mechanosensitivity by affecting R1-R2 switch dynamics and vinculin binding.

Journal of Cell Biology · Mar 6, 2023Peer-reviewedCancer Biology

The laminin-keratin link shields the nucleus from mechanical deformation and signalling

Z. Kechagia, P. Saez, M. Gomez-Gonzalez, M. Zamarbide, I. Andreu, T. Koorman, A. E. M. Beedle, P. W. B. Derksen, X. Trepat, M. Arroyo, P. Roca-Cusachs

This study shows laminin-111 shields the nucleus from mechanical deformation by linking integrin {beta}4 to keratin, affecting YAP localization and chromatin methylation in breast epithelial cells.

bioRxiv · Mar 1, 2022Cell Biology

Host targets of effectors of the lettuce downy mildew Bremia lactucae from cDNA-based yeast two-hybrid screening

A. J. E. Pelgrom, C.-N. Meisrimler, J. Elberse, T. Koorman, M. Boxem, G. Van den Ackerveken

The paper identifies 61 protein-protein interactions between Bremia lactucae effectors and lettuce proteins using yeast-two-hybrid screening, with four effector-target pairs showing nuclear relocalization.

bioRxiv · Dec 3, 2019Plant Biology