A. Elosegui-Artola

Cell response to extracellular matrix energy dissipation outweighs rigidity sensing

The paper shows that substrate energy dissipation suppresses YAP mechanosensing more than stiffness cues in cell mechanotransduction.

Lymph node expansion predicts magnitude of vaccine immune response

This study shows that lymph node expansion correlates with vaccine efficacy and immunization outcomes, with strong vaccines causing greater and longer-lasting LN expansion.

Matrix viscoelasticity controls spatio-temporal tissue organization

This study shows how matrix viscoelasticity influences tissue organization by causing symmetry breaking and branching in epithelial cell aggregates.

Mechanosensitivity of nucleocytoplasmic transport

Force application to the nucleus leads to nuclear accumulation of proteins by differentially affecting passive versus facilitated nucleocytoplasmic transport.

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

This study shows that the rate of force application drives cell mechanosensing through reinforcement and fluidization mechanisms.

Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts

This study shows that SHARPIN regulates collagen-specific mechanosensing in mammary fibroblasts by modulating integrin 11β1 activity and force transmission.

Mechanochemical feedback and control of endocytosis and membrane tension

The paper identifies a negative feedback loop between membrane tension and the CLIC/GEEC pathway mediated by vinculin and GBF1.