Author

Zengming Zhang

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ju CheniD· 2 shared Tongbin WuiD· 2 shared Xiaohai ZhouiD· 2 shared Yusu GuiD· 2 shared Zeyu CheniD· 2 shared Chao GaoiD· 1 shared Christopher M. AdamsiD· 1 shared Danni CheniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

Ju ChenORCID

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2 papers

Recent·Most cited

Transcriptional Readthrough at Atf4 Locus Suppresses Rps19bp1 and Impairs Heart Development

Zengming Zhang, Tongbin Wu, Zeyu Chen, Danni Chen, Zhengyu Liang, Christopher M. Adams, Yusu Gu, Mao Ye, Fhujjen Barroga, Sylvia Μ. Evans, Xiaohai Zhou, Ju Chen

The paper shows that cardiac defects in ATF4 knockout mice result from unintended Rps19bp1 downregulation due to transcriptional readthrough, not loss of ATF4 function.

Cardiovascular Research · Nov 14, 2025Peer-reviewedGenetics

RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing

Tongbin Wu, Zeyu Chen, Chao Gao, Elise V. Stanley, Zengming Zhang, Yusu Gu, Xiaohai Zhou, Ju Chen

This study shows RBPMS and RBPMS2 work together to regulate cardiac splicing, with double knockout mice dying in utero due to sarcomere disarray, while single knockouts survive with normal sarcomere structure.

Circulation Research · Aug 27, 2025Peer-reviewedDevelopmental Biology