Author

Zhaojun Wang

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Jingkun ZengiD· 2 shared Alan AshworthiD· 1 shared Arushi Singhal· 1 shared Austin R. HolubiD· 1 shared Beatrice CostaiD· 1 shared Chenglong XiaiD· 1 shared Daniel R. GulbransoniD· 1 shared Daniel Rosas-Rivera· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Jingkun ZengORCID

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Author profile →

2 papers

Recent·Most cited

Parkin deficiency rewires the genetic dependencies that govern neuronal survival

Shijie Wang, Daniel R. Gulbranson, Beatrice Costa, Lisa P. Elia, Zachary Tokuno, Reuben Thomas, Jingkun Zeng, Zhaojun Wang, Pinghan Zhao, Austin R. Holub, Yuhui Huang, Steven M. Finkbeiner

This study shows that Parkin deficiency alters genetic dependencies for neuronal survival, identifying key pathways and genes involved in this rewiring.

bioRxiv · Oct 28, 2026 · PreprintCell Biology

Selective Elimination of TP53 Mutant Cells by Transcript-Activated Chromatin Shredding

Jingkun Zeng, Zhiyuan Cheng, Huadong Chen, Zhaojun Wang, Jared Thompson, Kadin T. Crosby, Hesong Han, Arushi Singhal, Wayne Ngo, Chenglong Xia, Daniel Rosas-Rivera, Zeyuan Terry Zhang, Min Hyung Kang, Ying Mao, Morgan E. Diolaiti, , Jennifer A. Doudna

This paper develops a method to selectively kill cancer cells with TP53 mutations by using RNA-guided Cas12a2 to induce chromatin shredding through targeting cancer-specific transcripts.

Nature · Jun 8, 2026Peer-reviewedCell Biology