Author

Zhixing Li

Wenzhou Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Jianzhang WuiD· 2 shared Ling ZengiD· 2 shared Mao YeiD· 2 shared Neng LingiD· 2 shared Weibin LiuiD· 2 shared Xiaojing LiiD· 2 shared Xuanwen LiiD· 2 shared Yanchen ZhangiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Jianzhang WuORCID

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2 papers

Recent·Most cited

Immunometabolic Reprogramming by Thyroid-Stimulating Antibodies Drives Orbital Adipogenesis via Histone Lactylation in Thyroid Eye Disease

Yanchen Zhang, Neng Ling, Min Wu, Ling Zeng, Ben Chen, Weibin Liu, Zhixing Li, Yan Zhang, Xiaojing Li, Xuanwen Li, YiCheng Mao, Yate Huang, Shiguan Zhou, Shuhui Wan, Hongmei Wang, , Wencan Wu

This paper identifies metabolic reprogramming driven by thyroid-stimulating antibodies as a key mechanism in thyroid eye disease, showing lactate promotes adipogenesis through histone lactylation.

bioRxiv · Jul 30, 2026 · PreprintImmunology

TSHR-targeting nucleic acid aptamer treats Graves' ophthalmopathy via novel allosteric inhibition

Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, , Wencan Wu

This study develops YC3, a TSHR-targeting aptamer that inhibits TSHR signaling and treats Graves' ophthalmopathy by binding to a novel allosteric site.

Advanced Science · Oct 7, 2025Peer-reviewedBiochemistry