Author

Zhiying Yao

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Peiguo YangiD· 3 shared Yi LiuiD· 3 shared Yun ZhangiD· 3 shared Ziqiu WangiD· 3 shared Le Tian· 2 shared Qi CheniD· 2 shared Zhenshuo ZhuiD· 2 shared Haolong Lai· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCell Biology

Peiguo YangORCID

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3 papers

Recent·Most cited

Alphaviral nonstructural protein-host RBP co-condensation as a mechanism to sustain virus replication

Yi Liu, Zhiying Yao, Yun Zhang, Zhenshuo Zhu, Ziqiu Wang, Qi Chen, Zemin Yang, Yexuan He, Xiaoxin Chen, Le Tian, Jiang Du, Jinjun Wu, Hong Joo Kim, Jing Huang, Yongdeng Zhang, , Peiguo Yang

This study identifies nsP3-RBP co-condensation as a mechanism alphaviruses use to sustain replication, showing disruption of these condensates can inhibit viral replication.

Molecular Cell · May 21, 2026Peer-reviewedCell Biology

Alphaviral capsid proteins inhibit stress granule assembly via competitive RNA binding with G3BP1

Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang

This study identifies how alphavirus capsid proteins inhibit stress granule assembly by competing with G3BP1 for RNA binding, revealing a conserved mechanism across alphaviruses.

Advanced Science · Jan 27, 2026Peer-reviewedCell Biology

PARP10 condensation inhibits viral infection via targeting NAD+ homeostasis

Xiaoxin Chen, Qi Keng Xu, Yi Liu, Zhenshuo Zhu, Ziqiu Wang, Yun Zhang, Qi Chen, Le Tian, Zhiying Yao, Zhubing Shi, Peiguo Yang

This study identifies PARP10 condensation as an antiviral mechanism that disrupts NAD+ homeostasis to inhibit viral replication.

bioRxiv · Dec 25, 2025 · PreprintCell Biology