Author

Michael David Thompson

Centre for Genomic RegulationORCID 0000-0003-3858-7516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Approach:statistical model· 1

Frequent Co-Authors

Aleksandra BabichevaiD· 1 shared Christa CaggianoiD· 1 shared Christina M. PabelickiD· 1 shared Defne ErceleniD· 1 shared Ibrahim Shehata ElmadbouhiD· 1 shared Jason X.‐J. YuaniD· 1 shared Li WangiD· 1 shared Luke H. HoeppneriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

Aleksandra BabichevaORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintOct 14, 2025

Loss of miRNA-153 promotes endothelial-to-mesenchymal transition and compromises lung vascular integrity

Ibrahim Shehata Elmadbouh, Zhunran Zhong, Li Wang…·Aleksandra Babicheva

This study shows that loss of miR-153 promotes EndMT in lung endothelial cells, leading to vascular permeability and remodeling in pulmonary hypertension.

DOI 10.1101/2025.10.14.682369

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 30, 2024

Identifying novel genetic and phenotypic associations to genomic features by leveraging off-target reads in exome sequencing data

Defne Ercelen, Christa Caggiano, Richard Border…·Michael David Thompson

The paper uses unmapped reads from whole-exome sequencing data in the UK BioBank to construct features and identify 21 novel genetic loci associated with immune-related traits.

DOI 10.1101/2024.11.30.625754

humanwhole-exome sequencing

𝕏 PostBluesky