Structural insight into the transcription activation mechanism of the phage Mor/C family activators
Jing Shi, Zonghang Ye, Yirong Huang, Liqiao Xu, Simin Xu, Lihong Xie, Wei Chen, Lu Wang, Zhenzhen Feng, Qian Song, Shuang Wang, Yu Feng, Wei Lin
This study presents cryo-EM structures of Mor-TAC and C-TAC complexes, revealing a tetrameric binding mode and interactions with RNAP, elucidating the transcription activation mechanism of phage Mor/C family activators.
bioRxiv · May 2, 2025 · PreprintBiochemistry