Martin Schalling

The paper investigates microglial dysfunction in anorexia nervosa using patient-derived iPSCs and an animal model, finding altered synaptic interactions and signaling in hypothalamic circuits.

This study shows SARS-CoV-2 infection in human brain organoids leads to microglial synapse elimination, linking it to potential cognitive impairments post-COVID-19.

The study finds that rare copy number variants (CNVs) contribute to bipolar disorder risk primarily in schizoaffective disorder bipolar type cases, with differences in CNV burden and schizophrenia polygenic risk scores between subtypes.

The paper shows that polygenic scores for depression traits predict lithium response in bipolar disorder patients, with lower genetic load linked to better treatment outcomes.

This study finds that a higher genetic risk for schizophrenia is linked to poorer lithium response in bipolar disorder patients, suggesting potential for personalized treatment strategies.